7號染色體開放閱讀框26抗體簡介說明
2021-07-08 14:29 來源:上海遠(yuǎn)慕生物試劑
產(chǎn)品名稱:7號染色體開放閱讀框26抗體
別名:Chromosome7openreadingframe26;MGC2718;UncharacterizedproteinC7orf26;CG026_HUMAN.
濃度:1mg/1ml
規(guī)格:0.2ml/200μg
抗體來源:Rabbit
克隆類型:polyclonal
交叉反應(yīng):Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit
產(chǎn)品類型:7號染色體開放閱讀框26抗體一抗
研究領(lǐng)域:細(xì)胞生物免疫學(xué)
蛋白分子量:predictedmolecularweight:50kDa
性狀:LyophilizedorLiquid
免疫原:KLHconjugatedsyntheticpeptidederivedfromhumanC7orf26
亞型:IgG
純化方法:affinitypurifiedbyProteinA
儲存液:Preservative:15mMSodiumAzide,Constituents:1%BSA,0.01MPBS,pH7.4
產(chǎn)品應(yīng)用:WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500
(石蠟切片需做抗原修復(fù))
notyettestedinotherapplications.
optimaldilutions/concentrationsshouldbedeterminedbytheenduser.
保存條件:Storeat-20°Cforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20°C.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4°C.
ImportantNoteThisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications.
產(chǎn)品介紹:Chromosome7hasbeenlinkedtoOsteogenesisimperfecta,Pendredsyndrome,Lissencephaly,CitrullinemiaandShwachman-Diamondsyndrome.Thedeletionofaportionoftheqarmofchromosome7isassociatedwithWilliams-Beurensyndrome,aconditioncharacterizedbymildmentalretardation,anunusualcomfortandfriendlinesswithstrangersandanelfinappearance.Deletionsofportionsoftheqarmofchromosome7arealsoseeninanumberofmyeloiddisordersincludingcasesofacutemyelogenousleukemiaandmyelodysplasia.TheC7orf26geneproducthasbeenprovisionallydesignatedC7orf26pendingfurthercharacterization.
Databaselinks:UniProtKB/Swiss-Prot:Q96N11.1
抗體的多樣性:
抗體的異質(zhì)性??贵w的組成極為復(fù)雜,是由成千上萬、多種多樣的免疫球蛋白(Ig)分子所組成。這些Ig分子在形狀、大小、結(jié)構(gòu)以及氨基酸的組成和排列上,既相似,又有差別。由于有差別,它們的電泳活性就有很大的變化。
因?yàn)榭贵w具有與抗原決定簇相對應(yīng)的結(jié)合部位(抗原結(jié)合簇),所以抗體與抗原的結(jié)合具有特異性。另一方面,抗體本身是一種蛋白質(zhì),具有本身的氨基酸組成、排列和立體結(jié)構(gòu),對異種動物來說,它又是抗原。各類Ig都具有可用血清學(xué)方法檢出的抗原特異性,它們表現(xiàn)出不同的血清學(xué)類型。