黄片日韩欧美一级,亚洲国产成人精品电影,北岛玲日韩精品一区二区三区

歡迎來到上海遠(yuǎn)慕生物科技有限公司官方網(wǎng)站！

設(shè)為首頁加入收藏聯(lián)系我們

13310162040

產(chǎn)品分類

促銷產(chǎn)品

化學(xué)試劑 > 生化試劑 > 小分子抑制劑

產(chǎn)品名稱：	EPZ005687
產(chǎn)品編號：	AS-0258
別名：	EPZ005687 抑制劑
英文名：	1-cyclopentyl-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-6-[4-(morpholin-4-ylmethyl)phenyl]indazole-4-carboxamide
CAS號：	1396772-26-1
分子式：	C₃₂H₃₇N₅O₃
分子量：	539.67

大包裝詢價(jià)

EPZ005687 is a potent inhibitor of EZH2 (K(i) of 24 nM). EPZ005687 has greater than 500-fold selectivity against 15 other protein methyltransferases and has 50-fold selectivity against the closely related enzyme EZH1. The compound reduces H3K27 methylation in various lymphoma cells; this translates into apoptotic cell killing in heterozygous Tyr641 or Ala677 mutant cells, with minimal effects on the proliferation of wild-type cells.