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組織蛋白酶E抗體說(shuō)明書

2021-06-24 13:23 來(lái)源:上海遠(yuǎn)慕生物試劑
英文名稱:Anti-CathepsinE
中文名:組織蛋白酶E抗體
別名:CathepsinE;CATE;CTSE;EC3.4.23.34;Erythrocytemembraneasparticproteinase.
規(guī)格:0.1ml/100μg,0.2ml/200μg
交叉反應(yīng):hu,rat,mo
產(chǎn)品類型:一抗
應(yīng)用領(lǐng)域:/合成與降解
蛋白分子:predictedmolecularweight:42kDa
濃度值:1mg/1ml
物理性狀:LyophilizedorLiquid
免疫原:KLHconjugatedsyntheticpeptidederivedfromhumanCathepsinEC-terminus
亞型:polyclonal
純化方法:affinitypurifiedbyProteinA
保存液:0.01MPBS,pH7.4with10mg/mlBSAand0.1%Sodiumazide
應(yīng)用技術(shù)://WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蠟切片需做抗原修復(fù))/notyettestedinotherapplications./optimaldilutions/concentrationsshouldbedeterminedbytheenduser.
保存環(huán)境:Storeat-20°Cforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20°C.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4°C.

產(chǎn)品介紹:CathepsinEisanintracellularasparticproteaseofthepepsinfamily,whichisstructurallyhighlyhomologoustothelysosomalasparticproteasecathepsinD.CathepsinEislessabundantthanCathepsinDandhasamorelimiteddistribution,whichincludeslymphoidtissues,gastrointestinaltracttissue,bloodcells,microgliaandactivatedBlymphocytes.ItisnotexpressedinrestingBlymphocytes.CathepsinEmayhavearoleinimmunefunction.ItismostlikelyinvolvedintheprocessingofantigenicpeptidesduringMHCclassII-mediatedantigenpresentation.Itmayalsoplayaroleinactivation-inducedlymphocytedepletioninthethymus,andinneuronaldegenerationandglialcellactivationinthebrain.
 
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